BAT Science - Recent publications

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Recent publications


Our Research and Development facility undertakes a variety of research projects using a broad range of scientific disciplines and collaborations.  We publish results from our research in a variety of external, peer-reviewed scientific / academic publications. Here is a brief account of our most recent publications.

Open access manuscripts are indicated with the icon OA

An approach to testing undiluted e-cigarette aerosol in vitro using 3D reconstituted human airway epithelium 
Toxicology In Vitro
Bishop, E., Haswell, L., Adamson, J., Costigan, S., Thorne, D., Gaca, M.
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Estimation of the Leukemia Risk in Human Populations Exposed to Benzene from Tobacco Smoke Using Epidemiological Data
Risk Analysis
Feibelkorn, S. Meredith, C.
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Extreme testing of undiluted e-cigarette aerosol in vitro using an Ames air-agar-interface technique
Mutation Research
Thorne, D. Hollings, M. Seymour, A. Adamson, J. Dalrymple, A. Ballantyne M. Gaca, M.
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Characterisation of the borgwaldt LM4E system for in vitro exposures to undiluted aerosols from next generation tobacco and nicotine products (NGPs)
Food and Chemical Toxicology
Adamson, J. Jaunky, T. Thorne, D. Gaca, M.
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In vitro RNA-seq-based toxicogenomics assessment shows reduced biological effect of tobacco heating products when compared to cigarette smoke.
Scientific Reports
Haswell, L. Corke, S. Verrastro, I. Baxter, A. Banerjee, A. Adamson, J. Jaunky, T. Proctor, C. Gaca, M. Minet, E.
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Alternative approaches for acute inhalation toxicity testing to address global regulatory and non-regulatory data requirements: An international workshop report
Toxicology in Vitro
Clippinger, A. Allen, D. Jarabek, A. Corvaro, M. Gaca, M. Gehen, S. Hotchkiss, J. Patlewicz, G. Melbourne, J. Hinderliter, P. Yoon, M. Huh, D. Lowit, A. Buckley, B. Bartels, M. BeruBe, K. Wilson, D. Indans, I, Mathieu, V.
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Comprehensive survey of radionuclides in contemporary smokeless tobacco products
Chemistry Central Journal
McAdam, K. Kimpton, H. Porter, A. Liu, C. Faizi, A. Mola, M. McAughey, J. Rodu, B.
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Effect of temperature and humidity on the gas–particle partitioning of nicotine in mainstream cigarette smoke: A diffusion denuder study
Journal of Aerosol Science
John, E. Coburn, S. Liu, C. McAughey, J. Mariner, D. McAdam, K. Sebestyen, Z. Bakos, I. Dobe, S.
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Influence of cigarette filter ventilation on smokers’ mouth level exposure to tar and nicotine
Regulatory Toxicology and Pharmacology
Caraway, J. Ashley, M. Bowman, S. Chen, P. Errington, G. Prasad, K. Nelson, P. Shepperd, C. Fearon, I.
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A pharmacokinetic study to examine nicotine delivery from e-cigarettes and a conventional cigarette in healthy subjects during a brief period of ad libitum use
International Journal of Clinical Trials
Fearon, I. Nides, M. Camacho, O. Eldridge, A. Murphy, J. Proctor, C.
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Headspace solid-phase microextraction coupled to comprehensive two-dimensional gas chromatography–time-of-flight mass spectrometry for the analysis of aerosol from tobacco heating product
Journal of Chromotography A
Savareear, B., Lizak, R., Brokl, M., Wright, C., Liu, C., Focant, J F.
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Thermal desorption comprehensive two-dimensional gas chromatography coupled to time of flight mass spectrometry for vapour phase mainstream tobacco smoke analysis
Journal of Chromotography A
Savareear, B., Brokl, M., Wright, C., Focant, J F.
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Glo Special Issue - Assessment of tobacco heating product THP1.0.
Regulatory Toxicology and Pharmacology, 2017
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Assessing modified risk tobacco and nicotine products: Description of the scientific framework and assessment of a closed modular electronic cigarette
Regulatory Toxicology and Pharmacology, 2017
Murphy, J. Gaca, M. Lowe, F. Minet, E. Breheny, D. Prasad, K. Camacho, O. Fearon, I. Liu, C. Wright, C. Mcadam, K. Proctor, C.

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A randomised, controlled, two-Centre open-label study in healthy Japanese subjects to evaluate the effect on biomarkers of exposure of switching from a conventional cigarette to a tobacco heating product
BMC Public Health, 2017
Gale, N., McEwan, M., Eldridge, A., Sherwood, N., Bowen, E., McDermott, S., Holmes, E., Hedge, A., Hossack, S., Camacho, O., Errington, G., McAughey, J., Murphy, J., Liu, C., Proctor, C., Fearon, I.
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A comparative assessment of e-cigarette aerosols and cigarette smoke on in vitro endothelial cell migration
Toxicology Letters, 2017
Taylor, M., Jaunky, T., Hewitt, K., Breheny, D., Lowe, F., Fearon, I., Gaca, M.
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A reference genome for Nicotiana tabacum enables map-based cloning of homeologous loci implicated in nitrogen utilization efficiency
BMC Genomics, 2017
Edwards, K. D., Fernandez-Pozo, N., Drake-Stowe, K., Humphry, M., Evans, A. D., Bombarely, A., Allen, F., Hurst, R., White, B., Kernodle, S. P., Bromley, J. R., Sanchez-Tamburrino, J.P., Lewis, R.S., Mueller, L.A.
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